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Pamela Clark
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Pamela Clark, CRNI, is a Nurse Supervisor for Accredo, a leader in specialty pharmacy care. She has more than 28 years of experience in infusion therapy and infusion education with both licensed nurses and patients. Her experience spans multiple infusion settings including: acute care, long-term care, home infusion, and ambulatory infusion care. She also has experience in oncology and oncology research.


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Reducing Hospitalization with Hypodermoclysis

An online continuing education course for nurses, medical health care professionals, and other interested individuals.

This instructional course has been designed to provide information regarding the use of hypodermoclysis, also known simply as clysis, to achieve rehydration in patients who might otherwise require hospitalization. Dehydration is a common occurrence, especially in the older population. Clysis is an optimal means of administering non-emergent subcutaneous parenteral fluids in a familiar, comfortable environment.

“Clysis” or subcutaneous rehydration intervention is cost-effective, easy to administer, and safer than intravenous rehydration, but many nurses are unfamiliar with the therapy. This course will prepare the licensed nurse to provide this valuable intervention, thereby decreasing the risk of hospitalization with its associated risks and costs.


Upon completion of this course, the participant will be able to:

  1. Identify at least 3 factors that contribute to dehydration in the elderly.
  2. Define hypodermoclysis.
  3. Describe the advantages, disadvantages, indications, and contraindications of hypodermoclysis.
  4. Describe the appropriate sites, solutions, volumes and rates for hypodermoclysis.
  5. Describe the procedure for hypodermoclysis administration.
  6. State at least 3 potential complications of hypodermoclysis.


Chapter 1
  • Scope of Problem
  • Contributing Factors
  • Signs and Symptoms
  • Assessment
Chapter 2
Hypodermoclysis Introduction
  • Advantages
  • Disadvantage
  • Indications
  • Contraindications
  • Use in Terminally Ill Patients
Chapter 3
Infusion Parameters
  • Sites
  • Solutions
  • Volume and Rate
  • Hyaluronidase
Chapter 4
  • Equipment
  • Procedures
Chapter 5
  • Systemic Complications
  • Local Complications
Chapter 6
Communication and Documentation

Course Snapshot

Cost: $ 20.00
Contact Hours: 1.5


After successful completion the licensed nurse: RN, LPN/LVN will receive 1.5 contact hours.  Provider approved by the California Board of Registered Nursing, Provider # CEP 15467 and by the Florida Board of Nursing,CE Broker Tracking # is 20-314620.

LPN, RN, Nurse Practitioner, and Clinical Nurse Specialist will receive 1.5 contact hours. Provider approved by the District of Columbia Board of Nursing, CE Broker Tracking # is 20-314620.

This document must be retained by the licensee for a period of four years after the course concludes.

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